Insulin Clinical Trials

187 recruitingLast updated: June 18, 2026

There are 187 actively recruiting insulin clinical trials across 35 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Aurora, Colorado, United States, Bethesda, Maryland, United States. Updated daily from ClinicalTrials.gov.


Insulin Trials at a Glance

187 actively recruiting trials for insulin are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 111 trials, with the heaviest enrollment activity in New York, Aurora, and Bethesda. Lead sponsors running insulin studies include Yale University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and Columbia University.

Treatments under study

About Insulin Clinical Trials

Looking for clinical trials for Insulin? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Insulin trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Insulin clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 187 trials

Recruiting

Mathematical Modeling of Blood Sugar and Hormone Responses in Insulin-Dependent Type 2 Diabetes

Type 2 DiabetesInsulin Dependent Diabetes
Clinical Nutrition Research Center, Illinois Institute of Technology25 enrolled1 locationNCT07650682
Recruiting

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

CancerInsulin ResistanceMetabolic Syndrome+2 more
National Institute of Environmental Health Sciences (NIEHS)725 enrolled1 locationNCT01143480
Recruiting
Not Applicable

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

Diabetes MellitusDiabetes Mellitus, Type 2Diabetes+8 more
University of Colorado, Denver240 enrolled2 locationsNCT07011147
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

HypertensionCardiovascular DiseaseAdrenal Gland Neoplasm+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,150 enrolled1 locationNCT03374215
Recruiting

Diagnosing and Treating Low Blood Sugar Levels

InsulinomaHypoglycemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT00001276
Recruiting
Not Applicable

Exercise Effects on Adipose Tissue Structure and Function

ObesityInsulin ResistanceWeight Loss+3 more
University of Michigan46 enrolled1 locationNCT04812314
Recruiting

Genetic Studies of Insulin and Diabetes

Diabetes MellitusSevere Insulin Resistance
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,200 enrolled1 locationNCT00001987
Recruiting

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

ObesityInsulin ResistanceMetabolic Disease+2 more
University of Michigan175 enrolled1 locationNCT06007404
Recruiting
Not Applicable

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

Insulin ResistanceDepression in AdultsHIV+1 more
Indiana University150 enrolled1 locationNCT07226128
Recruiting
Phase 1

Graded Insulin Suppression Test P&F

ObesityInsulin ResistanceHealthy+1 more
Columbia University15 enrolled1 locationNCT06592261
Recruiting
Not Applicable

Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes

PrediabetesPrediabetes (Insulin Resistance, Impaired Glucose Tolerance)Prediabetes or Diabetes
Shifa International Hospital105 enrolled1 locationNCT07618663
Recruiting
Phase 1

Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy

Breast CancerHER2-negative Breast CancerHyperinsulinism
Yale University20 enrolled1 locationNCT05989347
Recruiting
Not Applicable

Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy.

Liver Transplant SurgerySolid-organ TransplantationDiabetes (Insulin-requiring, Type 1 or Type 2)+3 more
Institute for Clinical and Experimental Medicine62 enrolled1 locationNCT07611721
Recruiting
Phase 1

Metabolic Effects of Angiotensin-(1-7)

ObesityInsulin ResistanceHypertension+1 more
Vanderbilt University26 enrolled1 locationNCT02646475
Recruiting
Phase 3

A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism

Tumor Hyperinsulinism (Tumor HI)
Rezolute16 enrolled13 locationsNCT06881992
Recruiting
Not Applicable

ED Diabetes Screening and Outpatient Care - Aim 3

Diabetes MellitusNon Insulin Dependent Diabetes Mellitus
NYU Langone Health200 enrolled1 locationNCT05899023
Recruiting
Not Applicable

PREdiabetes GLycemic Impact and Data Evaluation

Insulin ResistanceObesity, OverweightPre-diabetic
Nazarii Kobyliak80 enrolled2 locationsNCT07599072
Recruiting
Not Applicable

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

ObesityInsulin ResistanceMuscle Weakness+2 more
University of Colorado, Denver70 enrolled1 locationNCT06129110
Recruiting
Phase 2

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Partial LipodystrophyInsulin Receptor Mutation
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)25 enrolled1 locationNCT05470504
Recruiting

Safety and Efficacy of EUS-RFA in Pancreatic Insulinoma

Insulinoma; Pancreas
Sahlgrenska University Hospital20 enrolled1 locationNCT07585032