Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes

This study is testing a new experimental insulin-sensitizing drug (CIR-0602K) in people with Type 1 diabetes who are already using a closed-loop automated insulin delivery system (like a hybrid artificial pancreas). The goal is to see if the drug can help improve blood sugar control. **You may be eligible if...** - You are aged 18–45 with Type 1 diabetes for at least 1 year - Your HbA1c (average blood sugar) is below 10% - Your BMI is between 18–35, and you are either overweight or require higher insulin doses - You are currently using a Dexcom G7-compatible closed-loop insulin system - You have been on stable non-diabetes medications for 6 months **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have smoked tobacco in the past 2 years - You have a history of significant heart, liver, or other serious disease - You have a history of alcohol or drug abuse within the past 6 months - You have HIV Talk to your doctor to see if this trial is right for you.