RecruitingNCT06045923

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV

Sponsor

Centers for Disease Control and Prevention

Enrollment

100 participants

Start Date

Mar 17, 2023

Study Type

OBSERVATIONAL

Conditions

HIV Infections Monkeypox AIDS

Summary

The purpose of this study is to examine the extent of mpox viral spread and immunologic markers in people with advanced HIV. Study findings will enhance knowledge of mpox pathogenesis in severely immunocompromised people, which can inform treatment and prevention of severe illness and deaths associated with mpox in people with advanced HIV.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at the immune response and viral behavior in people who develop a severe form of mpox (formerly known as monkeypox). By studying how the immune system responds in serious cases, researchers hope to find better ways to treat and manage the disease. **You may be eligible if...** - You have been confirmed to have mpox (monkeypox) - Your case is classified as severe by your treating doctors - You are willing to provide blood or tissue samples for research **You may NOT be eligible if...** - Your mpox case is mild and does not meet the severity criteria - You are not able to provide informed consent - You are under 18 (unless the study includes minors with guardian consent) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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