AIDS Clinical Trials

10 recruiting

Frequently Asked Questions

Common questions about AIDS clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 54 trials

Recruiting
Phase 2

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

HIV InfectionAnal Squamous Cell CarcinomaStage II Rectal Cancer AJCC v8+7 more
National Cancer Institute (NCI)40 enrolled14 locationsNCT04929028
Recruiting
Not Applicable

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

HIV InfectionsAIDSVirologic Failure
Massachusetts General Hospital648 enrolled3 locationsNCT05373758
Recruiting
Not Applicable

Appalachian Partnership to Reduce Disparities (Aim 2)

HCVHIV/AIDSSTI
Wake Forest University Health Sciences141 enrolled1 locationNCT04378439
Recruiting
Not Applicable

MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM

HIV/AIDS
Columbia University500 enrolled1 locationNCT06741618
Recruiting
Not Applicable

MyPEEPS LITE Trial

HIV/AIDS
Columbia University3,200 enrolled2 locationsNCT06741631
Recruiting
Phase 3

Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia

Pneumocystis PneumoniaPneumocystisPneumocystis Jirovecii Infection+5 more
Todd C. Lee MD MPH FIDSA416 enrolled1 locationNCT04851015
Recruiting
Not Applicable

Screening for Hepatitis B, Hepatitis C and AIDS Viruses Using Dried Blood Spot

Hepatitis BHepatitis CAIDS
University Hospital, Rouen500 enrolled11 locationsNCT05390424
Recruiting
Phase 2

An Integrated Intervention Using a Pill Ingestible Sensor System

Medication AdherenceSocial Determinants of Health (SDOH)HIV/AIDS
University of California, Los Angeles110 enrolled1 locationNCT06480578
Recruiting
Phase 1

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

HIV InfectionRecurrent Non-Hodgkin LymphomaRefractory Non-Hodgkin Lymphoma+12 more
AIDS Malignancy Consortium20 enrolled5 locationsNCT05077527
Recruiting
Not Applicable

Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Pilot Study

HIV/AIDS
University of California, San Francisco60 enrolled1 locationNCT07298785
Recruiting

The DC Cohort Longitudinal HIV Status Neutral Study

HIVAIDS
George Washington University19,000 enrolled14 locationsNCT01206920
Recruiting
Not Applicable

SCOPE Analytic Treatment Interruption Protocol

HIV/AIDS
University of California, San Francisco40 enrolled1 locationNCT04359186
Recruiting
Not Applicable

An mHealth Intervention to Improve Outcomes for Women With HIV/AIDS

HIV/AIDS
University of Miami80 enrolled1 locationNCT03738410
Recruiting
Not Applicable

HIV Suicide Prevention With AI-DBT

HIVSuicidal Ideation and BehaviorAIDS (Acquired Immune Deficiency Syndrome)
Rutgers, The State University of New Jersey50 enrolled2 locationsNCT07339189
Recruiting
Not Applicable

ADELANTE: A Randomized Controlled Trial to Improve Engagement in Care for Latinos With HIV

HIV/AIDS
Massachusetts General Hospital250 enrolled2 locationsNCT06274632
Recruiting
Phase 3

Optimizing Tobacco Use Treatment for PLWHA

Nicotine DependenceHIV/AIDS
University of Pennsylvania340 enrolled2 locationsNCT04176172
Recruiting

Screening and Follow-up in Patients With HIV Infection Combined With Metabolic Associated Fatty Liver Disease

FibrosisNonalcoholic SteatohepatitisNonalcoholic Fatty Liver Disease+1 more
Peking Union Medical College Hospital200 enrolled1 locationNCT05330923
Recruiting
Not Applicable

Sustaining Innovative Tools to Expand Youth-Friendly HIV Self-Testing

HIV/AIDSSexually Transmitted Diseases
Washington University School of Medicine1,216 enrolled1 locationNCT07072481
Recruiting
Not Applicable

Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement

HIV/AIDS
University of California, San Diego360 enrolled1 locationNCT05509959
Recruiting
Not Applicable

INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)

Medication AdherenceHabitsHIV/AIDS
RAND550 enrolled1 locationNCT06949774