RecruitingNCT06050447

Factors Affecting the Results of Treatment of Patients With Colorectal Cancer


Sponsor

Immanuel Kant Baltic Federal University

Enrollment

1,200 participants

Start Date

Sep 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The study attempts to quantify the relative risks for mortality, anastomotic leakage and other early and late postoperative complications, recurrence rate, cancer-specific survival, recurrence-free survival after colorectal surgery for patients with colorectal cancer depending on the localization of the tumor.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Histologically proven primary adenocarcinoma of bowel;
  • All patients who have indications for surgical treatment of colorectal cancer based on the decision of the oncological council;
  • Signed informed consent with agreement to attend all study visits;

Exclusion Criteria5

  • Unresectable tumor or contradictions to surgery;
  • Indications for chemotherapy or radiation therapy prior to surgery;
  • Patient withdrawal from the trial or loss of follow-up;
  • Emergent operation;
  • Pregnancy.

Interventions

PROCEDURERight hemicolectomy

Resection of the caecum and ascending colon is appropriate for patients with tumors located anywhere from caecum to the transverse colon

PROCEDURELeft hemicolectomy

Resection of the sigmoid colon is appropriate for patients with tumors located anywhere from the distal transverse colon to the rectosigmoid junction.

PROCEDURESigmoid colon resection

Resection of the sigmoid colon is appropriate for patients with tumors located in the sigmoid colon

PROCEDUREAnterior resection of the rectum

AR is appropriate for tumors located in rectosigmoid junction and in the proximal rectum

PROCEDURELow anterior resection of the rectum

LAR is appropriate for tumors located in the middle and low rectum

PROCEDUREAbdominoperineal resection

APR is appropriate for distal rectal cancers that invade the external sphincter or the levator muscles

PROCEDURETotal Colectomy

Total abdominal colectomy may be indicated for patients with primary multiple cancer tumors


Locations(1)

Baltic Federal University

Kaliningrad, Kaliningrad Oblast, Russia

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NCT06050447


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