Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis
Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis (PROSECCO)
Helsinki University Central Hospital
900 participants
Nov 15, 2023
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to compare protocol based selective imaging to routine imaging in adult patients with suspected appendicitis. The main question\[s\] it aims to answer are: * Does protocol based selective imaging using clinical scoring affect clinical outcome? * Does protocol based selective observation combined with score based selective imaging affect clinical outcome? Participants will be randomized into three groups: * Selective imaging based on Adult Appendicitis Score * Selective observation based on Appendicitis Severity Score combined with selective imaging based on Adult Appendicitis Score * Routine imaging using ultrasound and/or computed tomography Researchers will compare selective imaging groups separately with routine imaging to see if number of negative appendectomies or number of complicated appendicitis is not significantly increased.
Eligibility
Inclusion Criteria1
- \- Suspicion of appendicitis
Exclusion Criteria6
- Time from symptom onset over 72 hours
- Age \<18 years
- Pregnancy, ruled out by serum or urine HCG measurement in 18- to 49-year-old women
- CT-scan or ultrasound already done within the last 3 days (72 hours)
- Clinical suspicion of other disease or other reason to perform imaging study
- Recruited earlier to the same trial
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Interventions
Abdominal ultrasound and/or abdominal CT
Abdominal imaging is done selectively based on Adult Appendicitis Score
Observation based on Appendicitis Severity Score combined Adult Appendicitis Score based selective abdominal imaging
Locations(3)
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NCT06083064