Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

This study is exploring whether a low dose of ketamine — a medication already used for pain and anesthesia — can quickly reduce suicidal thoughts in people who come to the emergency department in a mental health crisis. Researchers want to see if this approach is safe and helpful while patients await psychiatric care. **You may be eligible if...** - You are between 18 and 65 years old - You are experiencing active suicidal thoughts and require inpatient psychiatric stabilization - You are fully alert (Glasgow Coma Score of 15) - You are being admitted to the University of Kansas Medical Center's psychiatric unit **You may NOT be eligible if...** - You have a history of psychosis or schizophrenia - You have had manic or hypomanic symptoms in the past 4 weeks - You have a history of ketamine misuse or addiction - You have had a liver transplant - You are pregnant or breastfeeding - Your blood pressure is dangerously high or low - You tested positive for drugs or alcohol - You have an acute medical condition requiring hospitalization Talk to your doctor to see if this trial is right for you.