Suicide Clinical Trials

26 recruiting

Frequently Asked Questions

Common questions about Suicide clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 47 trials

Recruiting
Not Applicable

Get ActivE Study for At-risk Youth

AnhedoniaDepression and Suicide Ideation
University of Pittsburgh75 enrolled2 locationsNCT06829953
Recruiting
Not Applicable

Project HOPEFUL: A PN-RCT With Implementation Science

Quality of LifeMental HealthOlder Adults (50-90 Years)+4 more
University of Florida400 enrolled1 locationNCT07475039
Recruiting
Not Applicable

A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans

PTSDVeteransTBI+3 more
VA Office of Research and Development120 enrolled1 locationNCT05995678
Recruiting
Not Applicable

A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

Mental Health DisorderSuicideAnhedonia
Ksana Health78 enrolled1 locationNCT05920252
Recruiting
Not Applicable

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

Suicidal IdeationPosttraumatic Stress Disorder (PTSD)Suicide Attempt
Ohio State University190 enrolled1 locationNCT07238192
Recruiting
Phase 2

Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

DepressionSuicide
VA Eastern Colorado Health Care System472 enrolled1 locationNCT06375083
Recruiting
Not Applicable

Brief Cognitive Behavioral Therapy for People With Physical Disabilities

Disability PhysicalSuicideSuicidal Ideation+3 more
Ohio State University60 enrolled1 locationNCT05695430
Recruiting
Not Applicable

Teen Recovery Through Inspiration, Support, and Empowerment

AnxietySuicidal IdeationDepression Disorders+1 more
University of Texas Southwestern Medical Center40 enrolled1 locationNCT07170657
Recruiting

Natural History of Depression, Bipolar Disorder and Suicide Risk

Molecular Mechanisms of Pharmacological ActionDepressive SymptomsSuicide+18 more
National Institute of Mental Health (NIMH)500 enrolled1 locationNCT06462196
Recruiting
Not Applicable

Implementing Suicide Prevention Into Primary Care in Nepal

SuicidePrimary Care
Yale University147 enrolled1 locationNCT07362056
Recruiting
Not Applicable

Integrated Suicide & Trauma Therapy for Suicide Risk

SuicideMajor Depressive DisorderTrauma
Unity Health Toronto20 enrolled1 locationNCT05613972
Recruiting
Phase 2

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

DepressionDepressive DisorderMolecular Mechanisms of Pharmacological Action+10 more
National Institute of Mental Health (NIMH)50 enrolled1 locationNCT06511908
Recruiting
Not Applicable

Safety Planning and Cognitive Behavioral Therapy for Adolescent Suicide Prevention in Mozambique

Suicide Prevention
University of Washington2,100 enrolled7 locationsNCT06465381
Recruiting
Phase 2

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial

SuicideMajor Depressive DisorderTreatment Resistant Depression
University Health Network, Toronto110 enrolled1 locationNCT06480500
Recruiting

Long-term Observation of Participants With Mood Disorders

DepressionSuicide Risk
National Institute of Mental Health (NIMH)1,000 enrolled1 locationNCT04877977
Recruiting
Not Applicable

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

Suicide AttemptsSuicidal IdeationSuicide and Self-harm+1 more
Seattle Children's Hospital306 enrolled2 locationsNCT05078970
Recruiting
Not Applicable

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

SuicideBereavement
University of Pittsburgh169 enrolled1 locationNCT06191484
Recruiting
Not Applicable

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

SuicideSuicidal Ideation
Elizabeth Arnold1,485 enrolled3 locationsNCT05869552
Recruiting
Not Applicable

WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

DepressionSuicidal IdeationSuicide, Attempted
Weill Medical College of Cornell University115 enrolled2 locationsNCT05183230
Recruiting
Not Applicable

Mobile Intervention for Suicidal Thoughts

Suicide
VA Office of Research and Development50 enrolled1 locationNCT06593379