RecruitingPhase 4NCT06093932

Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial

Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized, Multicenter, Double-blind, Placebo-controlled Trial


Sponsor

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Enrollment

100 participants

Start Date

Apr 7, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is: 1. To evaluate the efficacy of Songling Xuemaikang Capsules(SLXMKC) with grade 1 hypertension. 2. To reveal the potiential effects of SLXMKC on vascular function and structure of patients with grade 1 hypertension. 3. To explore the underlying mechanisms of the therapeutic effects of SLXMKC on the intervention of grade 1 hypertension.


Eligibility

Min Age: 35 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether Songling Xuemaikang — a traditional Chinese herbal medicine — can effectively lower blood pressure in people with mild (Grade 1) hypertension, either on its own or compared to standard blood pressure medications. **You may be eligible if...** - You are between 35 and 65 years old - You have Grade 1 essential hypertension (mildly elevated blood pressure with no known cause) - You are either not on blood pressure medication or have been taking it irregularly - You are willing to sign informed consent **You may NOT be eligible if...** - You have significant liver or kidney problems - You have gastrointestinal conditions affecting drug absorption - You are allergic to the study medication - You are pregnant, breastfeeding, or a man planning to father a child within 6 months - You have other serious illnesses, cancer, high cholesterol, or evidence of organ damage from high blood pressure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSongling Xuemaikang Capsules

3 capsules at a time, three times a day, duration: 12 weeks

BEHAVIORALLifestyle intervention

everyday, duration: 12 weeks

DRUGPlacebo

3 capsules at a time, three times a day, duration: 12 weeks


Locations(5)

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Beijing, Beijing Municipality, China

Suzhou Hosptial of Traditional Chinese Medicine

Suzhou, Jiangsu, China

Affiliated Hospital of Shandong University of Traditional Chinese Medicine

Jinan, Shandong, China

China Academy of Chinese Medical Sciences Xiyuan Hospital Jining Hospital

Jining, Shandong, China

China Academy of Chinese Medical Sciences Xiyuan Hospital Shanxi Hospital

Taiyuan, Shanxi, China

View Full Details on ClinicalTrials.gov

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NCT06093932


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