Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

This study is examining how sensation (the ability to feel touch) changes and recovers over time in people who have had mastectomy surgery — either for breast cancer or gender-affirming reasons. The goal is to better understand nerve regeneration after surgery, which could lead to improved surgical techniques. **You may be eligible if...** - You are over 18 years old - You are scheduled for a gender-affirming mastectomy or a nipple-sparing mastectomy (with reconstruction using implants or your own tissue) - You are willing and able to give informed consent **You may NOT be eligible if...** - You have a nerve condition that prevents accurate sensation testing - You are taking medications known to affect nerve growth or cause nerve damage - You are having two different types of reconstruction on each side (one with and one without nerve repair) - Your surgeon determines you are not a suitable candidate Talk to your doctor to see if this trial is right for you.