Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer

This study is testing a special foam-based drain (called eso-SPONGE or endoluminal vacuum therapy) placed inside the throat after surgery for esophageal cancer. The goal is to prevent a serious complication called anastomotic leakage — where the surgically connected tissue doesn't seal properly — which can be life-threatening. **You may be eligible if...** - You are 18 years or older - You are scheduled for a specific minimally invasive esophageal cancer surgery (called laparoscopic or robotic Ivor Lewis esophagectomy) - You are able to understand and sign a consent form - You are willing and able to follow the study's requirements **You may NOT be eligible if...** - You need open (non-minimally invasive) esophageal surgery - You need emergency esophageal surgery - You have blood clotting problems - You are pregnant, breastfeeding, or may be pregnant - You have bleeding in your esophagus due to varicose-like veins - You are allergic to any components of the device - You are currently participating in another clinical trial Talk to your doctor to see if this trial is right for you.