The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease

This study looks at how HIV infection and fatty liver disease (a buildup of fat in the liver) interact, and how the gut microbiome and body chemistry play a role. Researchers want to understand why people with HIV are more likely to develop liver problems. **You may be eligible if:** - You have one or more signs of metabolic syndrome (such as diabetes, high triglycerides, low good cholesterol, or high blood pressure) - OR you have been diagnosed with non-alcoholic fatty liver disease (NAFLD) - OR you have HIV and are on stable antiretroviral therapy **You may NOT be eligible if:** - You have other causes of liver disease (such as heavy alcohol use, hepatitis B or C, or certain medications that damage the liver) - You have had a liver transplant - You are pregnant - Specific additional medical or lab conditions identified at screening Talk to your doctor to see if this trial is right for you.