RecruitingNot ApplicableNCT06128720

Hyperbaric Oxygen Therapy for Optic Neuropathies

A Randomized, Sham Controlled, Masked Phase II Study to Evaluate the Neuroprotective Effect of Hyperbaric Oxygen Therapy on Optic Neuropathy


Sponsor

Stanford University

Enrollment

60 participants

Start Date

Nov 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing hyperbaric oxygen therapy (breathing pure oxygen inside a pressurized chamber) as a treatment for optic neuropathies — conditions where the nerve that connects the eye to the brain is damaged, causing vision loss. **You may be eligible if:** - You are 18 or older - You have clinical evidence of optic neuropathy (nerve damage to the eye) - You can follow the study schedule and attend all visits - You can give informed consent (or have it read to you if your vision is too impaired) **You may NOT be eligible if:** - You cannot follow study procedures or follow-up visits - You have clouding of the cornea or other clarity issues in the eye - You have participated in another drug trial in the past 3 months - You are pregnant or breastfeeding - You are a child or in a coma - You have claustrophobia or difficulty equalizing ear pressure - You have had hyperbaric oxygen therapy within the past 6 months - You abuse drugs or alcohol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEHyperbaric Oxygen

Participant will undergo 60 minutes of Hyperbaric oxygen at 1.5ATA while breathing 100% oxygen

DEVICESham Hyperbaric Oxygen

Participant will undergo 60 minutes of Sham Hyperbaric Oxygen at atmospheric pressure while breathing room air.


Locations(1)

Byers Eye Institute

Palo Alto, California, United States

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NCT06128720


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