Optic Neuropathy Clinical Trials

4 recruiting

Optic Neuropathy Trials at a Glance

10 actively recruiting trials for optic neuropathy are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Buenos Aires, Coral Springs, and Dubai. Lead sponsors running optic neuropathy studies include George Washington University, Hôpital Necker-Enfants Malades, and Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal.

Browse optic neuropathy trials by phase

Treatments under study

About Optic Neuropathy Clinical Trials

Looking for clinical trials for Optic Neuropathy? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Optic Neuropathy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Optic Neuropathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Repetitive Transorbital Alternating Current Stimulation for Optic Neuropathies

Optic Neuropathy
NYU Langone Health70 enrolled1 locationNCT06662448
Recruiting
Phase 1Phase 2

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
George Washington University24 enrolled1 locationNCT06792500
Recruiting
Not Applicable

New Non-invasive Modalities for Assessing Retinal Structure and Function

HemianopiaLeber Hereditary Optic NeuropathyIschemic Optic Neuropathy+2 more
Randy Kardon500 enrolled1 locationNCT03475173
Recruiting
Not Applicable

Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)

Healthy SubjectsLeber Hereditary Optic Neuropathy
Hôpital Necker-Enfants Malades90 enrolled1 locationNCT06682819
Recruiting

Optic Nerve Sheath Ultrasound in Giant Cell Arteritis

Giant Cell ArteritisAnterior Ischemic Optic NeuropathyOptic Neuropathy, Ischemic
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal285 enrolled6 locationsNCT05749094
Recruiting
Not Applicable

Optic Nerve Injury in Obstructive Sleep Apnea Patients

Obstructive Sleep Apnea (OSA)Ischemic Optic Neuropathy/Optic Nerve Stroke
Nanjing Medical University80 enrolled1 locationNCT06748703
Recruiting
Not Applicable

Hyperbaric Oxygen Therapy for Optic Neuropathies

GlaucomaOptic Neuropathy
Stanford University60 enrolled1 locationNCT06128720
Recruiting
Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION

Retinitis PigmentosaMacular DegenerationDiabetic Retinopathy+3 more
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled2 locationsNCT05147701
Recruiting
Not Applicable

Stem Cell Ophthalmology Treatment Study II

Age-Related Macular DegenerationRetinitis PigmentosaMacular Degeneration+15 more
MD Stem Cells500 enrolled4 locationsNCT03011541
Recruiting
Phase 2Phase 3

Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy

Leber's Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company102 enrolled1 locationNCT04912843