RecruitingNot ApplicableNCT06141135

GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial


Sponsor

Genomic Prediction Inc.

Enrollment

240 participants

Start Date

Nov 15, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40 years of age.


Eligibility

Sex: FEMALEMin Age: 35 YearsMax Age: 40 Years

Inclusion Criteria5

  • Women undergoing IVF of between 35 and 40 years of age at IVF cycle start
  • Utilization of Intracytoplasmic Sperm Injection ICSI (recommended) or ---Traditional IVF
  • Utilization of ejaculated or testicular sperm
  • Utilization of autologous or donor sperm
  • All Controlled Ovarian Hyperstimulation (COH) protocols

Exclusion Criteria6

  • Utilization of donor oocytes
  • Utilization of gestational carrier
  • Recurrent Pregnancy Loss (RPL) defined as ≥ 3 consecutive miscarriages
  • Recurrent Implantation Failure (RIF) defined as ≥ 3 more failed embryo transfers
  • Preimplantation genetic testing for monogenic/single gene disorders (PGT-M)
  • Translocation carriers

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Interventions

OTHERPreimplantation genetic testing for aneuploidy (PGTA)

24 chromosome screening for aneuploidy in the preimplantation embryo(blastocyst stage)


Locations(1)

Boston IVF

Waltham, Massachusetts, United States

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NCT06141135


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