RecruitingPhase 4NCT06144125

Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Cardiac Surgery

Prothrombin Complex Concentrate and Fresh Frozen Plasma in Viscoelastic Test-based Goal-directed Bleeding Management in Cardiac Surgery


Sponsor

Konkuk University Medical Center

Enrollment

100 participants

Start Date

Mar 27, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for cardiac surgery.


Eligibility

Min Age: 20 YearsMax Age: 75 Years

Inclusion Criteria1

  • patients undergoing cardiac surgery

Exclusion Criteria3

  • thrombocytopenia
  • oral anti-coagulant
  • anti platelet agents

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Interventions

BIOLOGICALfresh frozen plasma

transfusion of fresh frozen plasma

BIOLOGICALprothrombin complex concentrate

prothrombin complex concentrate administration


Locations(1)

Konkuk University Medical Center

Seoul, Seoul, South Korea

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NCT06144125


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