Cardiac Valve Disease Clinical Trials

7 recruitingLast updated: June 18, 2026

There are 7 actively recruiting cardiac valve disease clinical trials across 23 countries. Studies span Not Applicable, Phase 4. Top locations include Toulouse, France, Milan, Italy, Ancona, Italy. Updated daily from ClinicalTrials.gov.


Cardiac Valve Disease Trials at a Glance

7 actively recruiting trials for cardiac valve disease are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Toulouse, Milan, and Ancona. Lead sponsors running cardiac valve disease studies include Centre Chirurgical Marie Lannelongue, Corcym S.r.l, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse cardiac valve disease trials by phase

Treatments under study

About Cardiac Valve Disease Clinical Trials

Looking for clinical trials for Cardiac Valve Disease? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiac Valve Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiac Valve Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Phase 4

Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Cardiac Surgery

Cardiac Valve Disease
Konkuk University Medical Center100 enrolled1 locationNCT06144125
Recruiting
Not Applicable

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

Thoracic Aortic AneurysmCardiac Valve DiseaseAortic Aneurysm and Dissection+1 more
Petrovsky National Research Centre of Surgery50 enrolled1 locationNCT06336213
Recruiting

Cardiac Biomarkers for the Quantification of Myocardial Damage After Cardiac Surgery

Cardiac Valve Disease
Jena University Hospital100 enrolled5 locationsNCT06066970
Recruiting

Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients

Physical DisabilityFragilityCardiac Valve Disease+1 more
University of Sao Paulo General Hospital200 enrolled1 locationNCT06247358
Recruiting
Not Applicable

The Effects of 360-degree Virtual Reality on Pre-procedural Anxiety in Patients Awaiting Elective Cardiac Surgery Involving a Sternotomy

Aortic Valve DiseaseTricuspid Valve DiseaseMitral Valve Disease+1 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)100 enrolled1 locationNCT06001489
Recruiting

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

Cardiac Valve Disease
Corcym S.r.l2,150 enrolled52 locationsNCT05002543
Recruiting

European Multicentre Registry of Percutaneous Paravalvular Leak Closure

OutcomesQuality of LifeCardiac Valve Disease+3 more
Centre Chirurgical Marie Lannelongue400 enrolled33 locationsNCT05506293