RecruitingPhase 2NCT06144736

PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND

PRIMETEST II - Phase II Trial to Prospectively Test New Predictors for Recurrence in Patients With Clinical Stage II A/B Seminoma Treated With RA-RPLND


Sponsor

Heinrich-Heine University, Duesseldorf

Enrollment

60 participants

Start Date

Aug 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

PRIMETEST II is an interventional study involving low-volume metastatic seminoma. It explores a novel approach using robot-assisted primary retroperitoneal lymph node dissection, aiming to reduce long-term side effects and improve quality of life. By identifying factors predicting cancer recurrence, the study hopes to tailor treatments for better outcomes. The approach could potentially spare patients from chemotherapy induced long-term side effects while maintaining excellent survival rates, presenting a promising shift in testicular cancer care for this specific patient group.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin and a procedure called Robot-assisted retroperitoneal lymph node dissection for people with seminoma. The study is currently recruiting participants at 1 location. People eligible for this study include men aged 18 Years to 99 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERobot-assisted retroperitoneal lymph node dissection

Robot-assisted, if possibe ipsilateral nerve-sparing, retroperitoneal lymph node dissection and metastasis resection in a unilateral dissection field ("template")

DRUGAdjuvant therapy with one cycle of cisplatin, etoposide and bleomycin

The patient is given the option for an adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin two to four weeks after RA-RPLND


Locations(1)

University Hospital of Duesseldorf

Düsseldorf, Germany

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NCT06144736


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