The Role of Histamine in Muscle Protein Synthesis Following Resistance Training
The Role of Histamine in Muscle Protein Synthesis Following Chronic Resistance Training
University Ghent
50 participants
Sep 1, 2023
INTERVENTIONAL
Conditions
Summary
Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.
Eligibility
Inclusion Criteria3
- Male
- years
- Not to medium physically active
Exclusion Criteria7
- Smoking
- Chronic disease
- High blood pressure
- Supplement or medication intake
- Seasonal allergies
- Vegetarian / vegan
- Resistance trained
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Interventions
Oral placebo
H1 blockade: oral blockade with 180mg Fexofenadine
Resistance training: lower body exercise
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06152497