RecruitingNCT06164483

Auditory Functions in Patients With Multiple Sclerosis

Electrophysiological Studies of Auditory Functions and CSF Analyses in Patients With Multiple Sclerosis


Sponsor

University of Catania

Enrollment

30 participants

Start Date

Oct 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test, speech perception test, Auditory Brain Response (ABR) and Distortion Product Otoacustic Emission (DPOAE). CSF will be collected by lumbar puncture and analyzed looking for inflammatory markers. The results of DPOAE and CSF will be correlated to identify statistically significant correlation.


Eligibility

Min Age: 20 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether people with multiple sclerosis (MS) — a disease that affects the brain and nerves — have changes in their hearing and auditory processing, even when standard hearing tests appear normal. Researchers use advanced tests to detect subtle hearing function differences. **You may be eligible if...** - You have a confirmed diagnosis of multiple sclerosis - You are 18–60 years old - You have no prior known hearing loss or ear disease **You may NOT be eligible if...** - You have known hearing problems unrelated to MS - You have had ear surgery or chronic ear infections - You are taking medications known to damage hearing (ototoxic drugs) - You have severe cognitive impairment that would affect testing Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTAuditory test

The patients will perform: Pure Tone Auditory test + Tympanometry and Stapedial Reflex * Speech Perception test * In case of tinnitus: tinnitus questionnaire and acuphenometry * DPOAEs * ABR

OTHERCSF sampling

Cerebrospinal Fluid will be collected by lumbar puncture and analyzed


Locations(1)

Arianna Di Stadio

Catania, Sicily, Italy

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NCT06164483


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