RecruitingNCT06167135

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort

Polycystic Ovary Syndrome, Insulin Resistance, Infertility, Obesity, and the Associated Mitochondrial Dysfunction With These Disorders in Hungarian Patients


Sponsor

Semmelweis University

Enrollment

150 participants

Start Date

Sep 10, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned. During the research biomarkers already with mitochondrial dysfunction in the scientific literature and common mtDNA abnormalities (deletions, point mutations, copy number changes, etc.) are examined.


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is building a patient registry to better understand the relationship between polycystic ovary syndrome (PCOS), insulin resistance, mitochondrial dysfunction (when the body's cells don't produce energy properly), obesity, and fertility problems. Researchers hope to find patterns that explain why these conditions often occur together. **You may be eligible if...** - You have been diagnosed with PCOS or insulin resistance, especially alongside other health problems and signs of mitochondrial dysfunction - You have a history of fertility problems linked to mitochondrial dysfunction - You have a known history of mitochondrial dysfunction along with PCOS or insulin resistance - You are generally healthy enough to participate safely **You may NOT be eligible if...** - You are unwilling to cooperate with the study procedures - You decline to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Semmelweis University

Budapest, Hungary

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NCT06167135


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