Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Effect of Individualized High Positive End-expiratory Pressure on Postoperative Pulmonary Rate in Laparoscopic Bariatric Surgeries
Ain Shams University
50 participants
Oct 1, 2023
INTERVENTIONAL
Conditions
Summary
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications
Eligibility
Inclusion Criteria5
- Patients were eligible for participation if the met the following criteria
- Age between 18 and 60 years old.
- Body mass index > 40
- Laparoscopic bariatric elective surgery under general anesthesia.
- ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.
Exclusion Criteria5
- Previous lung surgery
- ASA status III or IV.
- Moderate to severe obstructive or restrictive lung disease .
- Persistant intraoperative hemodynamic instability .
- Need for postoperative mechanical ventilation
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Interventions
the Intraoperative PEEP will be titrated to best static compliance for each patient
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06168162