RecruitingNot ApplicableNCT07104825

Autonomic Neural Blockade in Bariatric Surgery

Autonomic Neural Blockade During Sleeve Gastrectomy and Gastric Bypass: A Randomized Controlled Trial Evaluating Pain and Nausea After Bariatric Surgery


Sponsor

Endeavor Health

Enrollment

200 participants

Start Date

Feb 5, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to evaluate if autonomic nerve block (ANB- blocking pain and nausea signals) decreases pain and anti-nausea medication requirements as well as the experience of pain/nausea during the first 72 hours after sleeve gastrectomy or gastric bypass surgery. Participants will be randomly assigned either to the standard of care or the ANB group before surgery. As part of standard of care, in both groups, laparoscopic bariatric surgery will be initiated with local anesthetic injected into the abdominal wall. In the ANB group, participants will be given an additional injection of local anesthetic medication to block nerves on and around the stomach.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Intraoperative autonomic neural blockade (ANB) and a procedure called Laparoscopic Standard of Care Abdominal Wall Block for people with bariatric surgery candidate, nausea and vomiting, postoperative, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREIntraoperative autonomic neural blockade (ANB)

Local anesthetic block of the neurovascular tissue along the lesser curve of the stomach and celiac trunk during sleeve gastrectomy or gastric bypass surgery.

PROCEDURELaparoscopic Standard of Care Abdominal Wall Block

Administration of local anesthetic to abdominal incisions (standard of care)


Locations(1)

Endeavor Health

Evanston, Illinois, United States

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NCT07104825


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