Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis

This early-phase trial tests a new single-dose treatment (SBT777101) for rheumatoid arthritis (RA) — a condition where the immune system attacks the joints, causing pain and swelling — in patients who have not had enough relief from existing treatments. **You may be eligible if...** - You have been diagnosed with moderate-to-severe rheumatoid arthritis in adulthood - Your RA is currently active (painful, swollen joints) - Your RA medications have been at a stable dose for at least 30 days - Previous RA treatments have not worked well enough or caused side effects you couldn't tolerate - Your BMI is below 35 - You agree to use effective contraception during the study **You may NOT be eligible if...** - You had major surgery in the last 12 weeks or plan surgery in the next year - You have uncontrolled heart, lung, kidney, or liver disease - You have an active infection or a history of repeated infections - You have untreated latent tuberculosis (TB) - You have a weakened immune system or an immune deficiency condition - You have another type of inflammatory joint disease (other than RA) Talk to your doctor to see if this trial is right for you.