aiTBS for NSSI and Suicide in Adolescent Depression

This study tests a non-invasive brain stimulation technique called accelerated intermittent theta burst stimulation (aiTBS) — a type of magnetic therapy applied to the scalp — in hospitalized teenagers with severe depression who are injuring themselves (self-harm). The goal is to quickly reduce depression and self-harm behaviors. **You may be eligible if...** - You are between 12 and 18 years old with a guardian available to monitor you - You have been diagnosed with major depressive disorder - You have a depression score of 18 or higher on a standard scale - You are currently hospitalized and have had two or more self-harm episodes in the past week **You may NOT be eligible if...** - You have a metal implant in your head or a pacemaker (which is unsafe for magnetic stimulation) - You have a history of seizures or epilepsy - You have a condition where the brain stimulation would be unsafe Talk to your doctor to see if this trial is right for you.