Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Improving Reading Competence in Aphasia With Combined Aerobic Exercise and Phono-Motor Treatment
Kessler Foundation
70 participants
Apr 18, 2024
INTERVENTIONAL
Conditions
Summary
The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.
Eligibility
Inclusion Criteria5
- fluent and literate in English prior to stroke
- st ever stroke
- more than 3 months post-stroke
- post-stroke reading deficits, defined as reading aloud accuracy <83% for single words or <65% for readable nonwords
- living within a 50-mile radius from Kessler Foundation.
Exclusion Criteria5
- contraindication to MRI
- prior neurological disease
- developmental learning or reading disability (i.e., developmental dyslexia)
- contraindication to exercise
- concurrent speech and language therapy
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Interventions
The goal of PMT is to build orthographic and phonological awareness and phonological sequence knowledge. During PMT, participants will complete a series of tasks manipulating minimal sound units (consonants (C) \& vowels (V)), combining these units into syllables (CVC, CVCC, CCVC) and syllable sequences (real words and readable nonwords). PMT will aim to engage 5 modalities: visual, acoustic, tactile kinesthetic, motor, and orthographic. Multisyllabic stimuli used during treatment will consist of 40 real words and 68 readable nonword letter strings.
Stationary ergometer cycling at 60% heart rate range for 20 minutes, plus 5 minutes of warm up and cool down.
Light stretching activities targeting the head/neck, shoulder, elbow/forearm, hand/wrist, trunk/hip, ankle/foot.
Locations(1)
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NCT06213272