Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
University of Maryland, Baltimore
78 participants
Apr 9, 2024
INTERVENTIONAL
Conditions
Summary
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Eligibility
Inclusion Criteria4
- Age (18-88 years)
- English speaker (written and spoken)
- Temporal Mandibular Disorder (TMD) for at least 3 months
- TMD Grade Chronic Pain Scale (GCPS) ≥ 0
Exclusion Criteria18
- Present or past degenerative neuromuscular disease
- Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years
- Cervical pain (e.g. stenosis, radiculopathy)
- Any personal (or family first degree) history of mania, schizophrenia, or other psychoses
- Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years.
- Use of Antipsychotics (e.g., Risperdal, Ability and clozaril)Lifetime alcohol/drug dependence or alcohol/drug abuse in past 3 months
- Pregnancy or breast feeding
- Color-blindness
- Impaired or uncorrected hearing
- Non-dominant hand
- Any facial trauma that has occurred in the last 6 weeks
- History of a severe facial trauma in the last 2-3 months
- Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)
- Known history of severe motion sickness
- Non-removable head cover, artificial hair, certain types of braids or dreadlocks
- History of fainting
- History of angioedema
- Failed drug test (testing for opiates, cocaine, methamphetamines, and amphetamines)
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Interventions
Participants will use RelieVRx daily for 20min/day for 3 weeks
Participants will use Sham-VR, consisting of video, images, and sound in a head-mounted display but lack the "sense of presence" and immersive features of Active-VR (for example, scene changes with head movement). Participants will use the Sham-VR daily for 20min/day for 3 weeks
Participants will continue regular/usual care without any VR devices (goggles or audiovisual input)
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06214923