Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis

This observational study is looking at whether a special type of heart ultrasound analysis called deformation imaging (strain echocardiography) can detect early heart muscle dysfunction in people with peripheral artery disease (PAD) — a condition where blood flow in the leg arteries is reduced. Heart problems are common in PAD patients but may not always be obvious, and this study aims to identify them earlier using advanced imaging. **You may be eligible if...** - You have been diagnosed with lower limb artery disease (PAD) with any level of symptoms, OR - You are in the control group: aged 35 to 85 with at least one of the following — high blood pressure, diabetes, coronary artery disease, or you are a smoker **You may NOT be eligible if...** - You are under 35 or over 85 years old - You have a BMI of 40 or higher - You have a known history of heart failure - You have had a heart attack in the past 3 months - You have moderate to severe heart valve disease - You have a pacemaker or implanted cardiac device - You have severe lung disease (COPD or severe asthma) - You have significant kidney problems (eGFR below 30) - You have severe liver disease or certain blood disorders - You are currently undergoing cancer treatment or have had cancer within the past 5 years Talk to your doctor to see if this trial is right for you.