RecruitingNCT06221891

Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

Sponsor

Fifth Affiliated Hospital, Sun Yat-Sen University

Enrollment

500 participants

Start Date

Oct 1, 2023

Study Type

OBSERVATIONAL

Conditions

Chronic Kidney Diseases Left Ventricular Systolic Dysfunction

Summary

The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD). The main questions it aims to answer are: 1. If first-phase ejection fraction（EF1）could early detect the left ventricular systolic dysfunction in patients with CKD. 2. Whether EF1 can detect left ventricular systolic dysfunction in patients with CKD more sensitively than speckle-tracking echocardiography and myocardial work. Participants will need to cooperate to do an echocardiography. Researchers will compare healthy volunteers and patients with CKD to see if EF1 could early detect the left ventricular systolic dysfunction.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is using a special type of ultrasound to detect early damage to the heart's pumping function in people with chronic kidney disease (CKD), even before standard tests show a problem. The goal is to find heart problems earlier so they can be treated sooner. **You may be eligible if...** - You have been diagnosed with chronic kidney disease - You are currently hospitalized at the Fifth Affiliated Hospital of Sun Yat-sen University - Your heart's pumping function (ejection fraction) is 50% or higher **You may NOT be eligible if...** - You have primary high blood pressure, diabetes, or a congenital heart condition - You are pregnant or breastfeeding - Your ultrasound images are too unclear to analyze Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

The Fifth Affiliated Hospital of Sun Yat-sen University

Zhuhai, Guangdong, China

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NCT06221891

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