Left Ventricular Systolic Dysfunction Clinical Trials

6 recruitingLast updated: June 18, 2026

There are 6 actively recruiting left ventricular systolic dysfunction clinical trials across 37 countries. Studies span Phase 3, Phase 2, Phase 4. Top locations include Aurora, Colorado, United States, Boston, Massachusetts, United States, Ankara, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Left Ventricular Systolic Dysfunction Trials at a Glance

6 actively recruiting trials for left ventricular systolic dysfunction are listed on ClinicalTrialsFinder across 6 cities in 37 countries. The largest study group is Phase 3 with 3 trials, with the heaviest enrollment activity in Aurora, Boston, and Ankara. Lead sponsors running left ventricular systolic dysfunction studies include Bayer, Fifth Affiliated Hospital, Sun Yat-Sen University, and Mayo Clinic.

Browse left ventricular systolic dysfunction trials by phase

Treatments under study

About Left Ventricular Systolic Dysfunction Clinical Trials

Looking for clinical trials for Left Ventricular Systolic Dysfunction? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Left Ventricular Systolic Dysfunction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Left Ventricular Systolic Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 16 of 6 trials

Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 3

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer117 enrolled132 locationsNCT07192952
Recruiting
Phase 2Phase 3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled106 locationsNCT05714085
Recruiting

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

Left Ventricular Systolic Dysfunction
Mayo Clinic30 enrolled1 locationNCT06770062
Recruiting
Phase 4

Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure

Iron-deficiencyChronic Heart FailureLeft Ventricular Systolic Dysfunction
Raffaele De Caterina60 enrolled1 locationNCT06270498
Recruiting

Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

Chronic Kidney DiseasesLeft Ventricular Systolic Dysfunction
Fifth Affiliated Hospital, Sun Yat-Sen University500 enrolled1 locationNCT06221891