RecruitingNot ApplicableNCT06223672
Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study
Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study: Dietary Fat Quality and Cognitive Impairment
Sponsor
Ohio State University
Enrollment
88 participants
Start Date
Feb 7, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The proposed research is a randomized crossover trial designed to assess changes in postprandial cognitive function and the gut-brain axis in adults with subjective cognitive complaints who consume 1 study snack per day for 1 week.
Eligibility
Min Age: 40 YearsMax Age: 75 Years
Inclusion Criteria3
- Subjective cognitive impairment
- BMI ≥30 kg/m2
- HbA1C <6.5%
Exclusion Criteria18
- Diagnosis og cognitive impairment or dementia
- Montreal Cognitive Assessment (MoCA) score of <26
- Current or previous diagnosis of Diabetes or use of diabetes medications
- Current diagnosis of or current treatment of cancer other than non-melanoma skin cancer
- Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods
- Hyperthyroidism diagnosis
- Food Allergy or intolerances
- Any dietary restriction where consumption of the study foods, study meals/snack or meal challenge or any ingredient would be contraindicated
- Use of some oil supplements in the past 4 weeks prior to enrolling
- Pregnancy and lactation
- Inability to access veins for venipuncture
- Antibiotic use in the past month
- Psychostimulant or nootropic medication use
- Current use of supplements or medications for weight loss or following a weight loss program
- Severe or uncontrolled autoimmune diseases
- Current or previous diagnosis of severe kidney failure, liver cirrhosis and some pulmonary diseases
- Heart disease events (including stroke or heart attack) within last 3 months prior to enrollment
- Alcohol or drug abuse
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Interventions
OTHERWalnuts
56g of walnuts consumed each day for 7 days
OTHERSimply White Diary-free chocolate bar
68g of the white chocolate style-bar each day for 7 days
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06223672
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