RecruitingNot ApplicableNCT06268600

The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma

The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma: A Retrospective Study

Sponsor

Jiangxi Provincial Cancer Hospital

Enrollment

320 participants

Start Date

Jan 1, 2019

Study Type

INTERVENTIONAL

Conditions

Nasopharyngeal Cancer Nasopharyngeal Carcinoma Hypothyroidism

Summary

This study aimed to reduce radiation-induced thyroid injury without compromising control of the cervical region by optimizing the delineation of the cervical lymph node drainage area.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a modified radiation therapy approach designed to protect the thyroid gland while still delivering effective treatment for nasopharyngeal carcinoma (a type of head and neck cancer), to reduce the risk of thyroid problems after radiation. **You may be eligible if...** - You are between 18 and 70 years old - You have newly diagnosed nasopharyngeal carcinoma (confirmed by biopsy) - Your cancer is Stage I–IVa and has not spread to distant organs - You have normal thyroid function before treatment - Your blood counts and organ function meet the study requirements **You may NOT be eligible if...** - You already have a thyroid condition (hypothyroidism or hyperthyroidism) - You are pregnant or breastfeeding - You have another active cancer - Your overall health is too poor for full-dose radiation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

RADIATIONModified neck target volume delineation

Modified neck target volume delineation method was used to define the inner boundary of regions III and IVa as the outer edge of the common carotid artery.