Hypothyroidism Clinical Trials

23 recruiting

Hypothyroidism Trials at a Glance

32 actively recruiting trials for hypothyroidism are listed on ClinicalTrialsFinder across 6 cities in 20 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in Bologna, Seongnam-si, and Orange. Lead sponsors running hypothyroidism studies include IRCCS Azienda Ospedaliero-Universitaria di Bologna, Seoul National University Bundang Hospital, and All India Institute of Medical Sciences, Bhubaneswar.

Browse hypothyroidism trials by phase

Treatments under study

About Hypothyroidism Clinical Trials

Looking for clinical trials for Hypothyroidism? There are currently 23 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypothyroidism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypothyroidism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting

Natural History of Thyroid Function Disorders

HypothyroidismHyperthyroidismGrave's Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,500 enrolled1 locationNCT00001159
Recruiting
Not Applicable

Gluten Free Diet in Hashimoto's Hypothyroidism

HypothyroidismHashimoto Disease
The Cleveland Clinic50 enrolled1 locationNCT07060118
Recruiting
Phase 2Phase 3

Novel Approaches to the Treatment of Hypothyroidism

Hypothyroidism
UConn Health90 enrolled1 locationNCT06731764
Recruiting

Comparison of Levothyroxine Formulations in the Treatment of Congenital Hypothyroidism

Congenital Hypothyroidism
IRCCS Azienda Ospedaliero-Universitaria di Bologna120 enrolled1 locationNCT06724224
Recruiting

Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ Thyroid

Congenital Hypothyroidism
IRCCS Azienda Ospedaliero-Universitaria di Bologna350 enrolled1 locationNCT06728735
Recruiting
Phase 4

Dosing of LT4 in Older Individuals

Hypothyroidism
University of Pennsylvania228 enrolled1 locationNCT06073665
Recruiting

Physical Activity, Fatigue, Social Support, and Psychological Well-Being in Women With Primary Hypothyroidism

Hypothyroidism Primary
University of Oviedo96 enrolled1 locationNCT07408765
Recruiting

Comorbidities Resolution After MGB Surgery and Change in Body Composition

HypertensionNon-Alcoholic Fatty Liver DiseaseSleep Apnea+5 more
All India Institute of Medical Sciences, Bhubaneswar35 enrolled1 locationNCT06015620
Recruiting
Not Applicable

SNUH Immune Checkpoint Inhibitor-induced Hypothyroidism Recovery Trial

Hypothyroidism
Seoul National University Bundang Hospital107 enrolled1 locationNCT07421869
Recruiting

Infants With Primary Congenital Hypothyroidism and Development

Congenital Hypothyroidism
Nigde Omer Halisdemir University40 enrolled1 locationNCT07280104
Recruiting
Not Applicable

Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

Hypothyroidism
University of Michigan900 enrolled3 locationsNCT06629272
Recruiting
Not Applicable

Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism

Cardiac FunctionSubclinical HypothyroidismChildren+1 more
Tanta University40 enrolled1 locationNCT07393165
Recruiting
Not Applicable

Thyroid Hormone Replacement After Coronary Artery Bypass Grafting for Patients With Subclinical Hypothyroidism

Subclinical Hypothyroidism
Seoul National University Bundang Hospital338 enrolled1 locationNCT07380854
Recruiting

Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation

InfertilitySubclinical Hypothyroidism
Mỹ Đức Hospital900 enrolled2 locationsNCT07257250
Recruiting
Phase 2Phase 3

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism
AbbVie2,800 enrolled139 locationsNCT06345339
Recruiting
Not Applicable

Ayurvedic Diet in Myxedema

Hypothyroidism Primary
University of Copenhagen88 enrolled2 locationsNCT07323706
Recruiting

Improvement of Laboratory Diagnostics in Hypothyroid Patients Using Levothyroxine

Hypothyroidism
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)500 enrolled1 locationNCT06083636
Recruiting
Not Applicable

Periodization Resistance Training on Quality of Life in Females With Hypothyroidism

Hypothyroidism
Cairo University75 enrolled1 locationNCT06757712
Recruiting
Not Applicable

Patient-centered Dosage of Levothyroxine

Thyroid CancerThyroidHypothyroidism
University Hospital of North Norway240 enrolled3 locationsNCT06455371
Recruiting
Not Applicable

Prospective Evaluation of OptiThyDose

Graves DiseaseThyroid DiseasesCongenital Hypothyroidism
University Children's Hospital Basel150 enrolled2 locationsNCT06864351