RecruitingNCT06272864

BostonGene and Exigent Genomic INsight Study

BostonGene and Exigent Genomic INsight (BEGIN) Study: A Prospective Study of Comprehensive Molecular Testing in Advanced Cancer Patients in the Community Setting


Sponsor

BostonGene

Enrollment

400 participants

Start Date

Apr 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Patients must have a confirmed malignancy of:
  • Locally recurrent, unresectable, or metastatic breast cancer or; Unresectable stage III or metastatic non-small cell lung cancer or; Unresectable or metastatic melanoma or; Locally advanced or metastatic l sarcoma.
  • Life expectancy \> 3 months as per the treating physician
  • Willingness to provide informed consent
  • Living in the United States at time of enrollment
  • Agree to participate in genomic and molecular profiling

Locations(7)

Highlands Oncology Group

Rogers, Arkansas, United States

Stockton Hematology Oncology Medical Group

Stockton, California, United States

Fort Wayne Medical Oncology and Hematology

Fort Wayne, Indiana, United States

New Mexico Cancer Center

Albuquerque, New Mexico, United States

Oklahoma Cancer Specialists and Research Institute

Tulsa, Oklahoma, United States

Oncology Consultants

Houston, Texas, United States

Northwest Medical Specialities

Puyallup, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT06272864


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