RecruitingNCT06272864

BostonGene and Exigent Genomic INsight Study

BostonGene and Exigent Genomic INsight (BEGIN) Study: A Prospective Study of Comprehensive Molecular Testing in Advanced Cancer Patients in the Community Setting


Sponsor

BostonGene

Enrollment

400 participants

Start Date

Apr 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The BEGIN Study by BostonGene and Exigent Genomic INsight evaluates the efficacy of comprehensive molecular testing in advanced cancer patients. Using the BostonGene Tumor Portrait test, the study aims to identify actionable findings, assess feasibility, and determine patient enrollment in clinical trials. Four cohorts of 100 patients each will be studied over two years, focusing on treatment decisions and patient outcomes. This study seeks to demonstrate the clinical utility of genomic testing in guiding therapy for advanced cancer patients in community settings.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting genomic and molecular profiling data from people with advanced cancers — including breast cancer, lung cancer, melanoma, and sarcoma — to learn how tumor biology influences treatment outcomes. Participation involves providing tumor samples for genetic analysis. **You may be eligible if...** - You have advanced, unresectable, or metastatic breast cancer, non-small cell lung cancer, melanoma, or soft tissue sarcoma - Your life expectancy is greater than 3 months - You live in the United States - You are willing to share genetic and molecular data from your tumor **You may NOT be eligible if...** - You do not have one of the listed cancer types - You are not willing to participate in genomic profiling Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(7)

Highlands Oncology Group

Rogers, Arkansas, United States

Stockton Hematology Oncology Medical Group

Stockton, California, United States

Fort Wayne Medical Oncology and Hematology

Fort Wayne, Indiana, United States

New Mexico Cancer Center

Albuquerque, New Mexico, United States

Oklahoma Cancer Specialists and Research Institute

Tulsa, Oklahoma, United States

Oncology Consultants

Houston, Texas, United States

Northwest Medical Specialities

Puyallup, Washington, United States

View Full Details on ClinicalTrials.gov

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NCT06272864


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