Metformin IN Asthma for Overweight and Obese Individuals (MINA)

This study is testing whether metformin — a common diabetes medication — can improve asthma control in overweight and obese adults whose asthma is not well-controlled despite current treatment. Researchers believe metformin may reduce airway inflammation. **You may be eligible if...** - You are 18 or older - You have a doctor-diagnosed asthma on regular maintenance treatment - Your asthma is not well controlled (you score below 20 on the Asthma Control Test or had at least one flare requiring steroids in the past year) - Your BMI is 25 kg/m² or higher (overweight or obese) **You may NOT be eligible if...** - You are pregnant or planning to become pregnant - You have had a heart attack, stroke, or heart failure in the past 6 months - You have other chronic lung diseases such as COPD or pulmonary fibrosis - You are a current smoker or have a significant smoking history Talk to your doctor to see if this trial is right for you.