RecruitingNCT06286007

Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control

Sponsor

Hospital Clinico Universitario de Santiago

Enrollment

784 participants

Start Date

Dec 21, 2023

Study Type

OBSERVATIONAL

Conditions

Asthma RSV Infection Pertussis

Summary

The main objective is to estimate the annual symptomatic incidence of Bordetella pertussis and RSV infections in patients aged 18 years and over with asthma, which will be identified by PCR, for Bordetella pertussis and by PCR for RSV performed at a specific timepoint from onset of symptoms for each symptomatic Acute Respiratory Infection (ARI). A multicentre prospective cohort study will be undertaken in Spain. Thirty-five centres from different autonomous communities in Spain will participate in the study. Participants will be asked to report to the investigator if they experience an asthma exacerbation or symptoms of acute respiratory infection with 2 years follow up

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how often two infections — whooping cough (pertussis) and RSV (respiratory syncytial virus) — occur in adults with asthma and whether these infections worsen asthma symptoms or control. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with asthma for at least one year - You are willing to provide samples and come in for testing when you have an asthma flare-up or cold/respiratory symptoms **You may NOT be eligible if...** - You had whooping cough in the past 12 months - You currently have a respiratory infection (within the past 2 weeks) - You have another lung disease besides asthma, active cancer, or an alcohol or drug problem Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPCR

Depending on the symptoms presented and date of symptom onset, for pertussis, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 3 weeks For RSV, patients will undergo a nasopharyngeal swab specimen for PCR if onset of the symptoms was within the past 72 hours.

Locations(1)

Hospital Clínico Universitario de Santiago de Compostela

Santiago de Compostela, A Coruña, Spain

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NCT06286007

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