RecruitingNot ApplicableNCT06294184

TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.

Transcranial Direct Current Stimulation Interventions for Subthreshold Depressive Symptoms in Young Individuals.


Sponsor

Guangzhou Psychiatric Hospital

Enrollment

150 participants

Start Date

Nov 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is carried out.


Eligibility

Min Age: 12 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This study is testing transcranial direct current stimulation (tDCS) — a painless, low-level electrical scalp stimulation — in young people aged 12 to 25 who have mild depressive symptoms that don't yet meet the full criteria for major depression. The goal is to see whether this brain stimulation can reduce symptoms before they worsen. **You may be eligible if...** - You are between 12 and 25 years old - You are right-handed - You have 2–4 depressive symptoms lasting more than 1 week, or 5+ symptoms lasting 1–2 weeks (not quite meeting criteria for major depression) - Your depression score on the Hamilton scale (HAMD-24) is between 8 and 23 **You may NOT be eligible if...** - You meet full diagnostic criteria for major depression or have another DSM-5 psychiatric diagnosis - You have significant neurological, heart, or other serious medical conditions - You have metal implants in your head or a history of seizures Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEtdcs lDLPFC

The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3, cathode is on the FP2.

DEVICEtdcs rVLPFC

The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F6, cathode is on the FP1.

DEVICESham

The current only persist in the fisrt 30s, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3/F6, cathode is on the FP2/1.


Locations(1)

Guangzhou Brain hospital(Guangzhou Huiai Hospital)

Guangzhou, Guangdong, China

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NCT06294184


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