RecruitingNot ApplicableNCT06517121

tDCS in People With Subthreshold Depression

Personalised Transcranial Direct Current Stimulation to Reduce Daily Loneliness in People With Subthreshold Depression


Sponsor

Education University of Hong Kong

Enrollment

204 participants

Start Date

Jan 16, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation technique that passes a very mild electrical current through the scalp — in people with mild depressive symptoms that don't yet meet the full criteria for clinical depression (called "subthreshold depression"). The goal is to see whether tDCS can reduce these symptoms before they worsen. **You may be eligible if...** - You have mild depressive symptoms that qualify as "subthreshold depression" (below the level of a full clinical depression diagnosis) - You have no history of learning disabilities, major psychiatric disorders (including Major Depressive Disorder), or neurological conditions - You have completed at least primary school education **You may NOT be eligible if...** - You are currently on medications or undergoing treatments that affect brain or mood function (within the 2 weeks before the study) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEPersonalized Experimental Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity over personalized brain regions based on the particular neural correlates of socio-affective processing.

DEVICESham Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants assigned to the sham control group will only receive 30 seconds of active stimulation.

DEVICEConventional Experimental Transcranial Direct Current Stimulation (tDCS)

This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity with anode placed over F3.


Locations(1)

The Education University of Hong Kong

Hong Kong, Hong Kong

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06517121


Related Trials