RecruitingNCT06309511

Subendocardial Viability Ratio in Hypertension


Sponsor

Istituto Auxologico Italiano

Enrollment

3,000 participants

Start Date

Oct 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension. The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry. The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase. The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at the relationship between high blood pressure (hypertension) and a measure called the subendocardial viability ratio — an indicator of how well the heart muscle is receiving blood flow, particularly in the innermost layer of the heart wall, which is most vulnerable to reduced blood supply. **You may be eligible if...** - You have been diagnosed with hypertension (high blood pressure) **You may NOT be eligible if...** - You have atrial fibrillation (an irregular heart rhythm), which would interfere with the measurements taken in this study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTArterial tonometry

Arterial transcutaneous tonometry


Locations(5)

Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi"

Mascalucia, Catania, Italy

Unità Operativa Semplice Dipartimentale Ipertensione Arteriosa "Anna Maria Pirrelli", Università degli Studi di Bari "Aldo Moro". Policlinico Consorziale di Bari

Bari, Italy

Istituto Auxologico Italiano IRCCS

Milan, Italy

Medicina II Cardiovascolare, AUSL-IRCCS di Reggio Emilia

Reggio Emilia, Italy

Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università degli studi di Trieste

Trieste, Italy

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NCT06309511


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