Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
Istituto Auxologico Italiano
65 participants
Feb 29, 2024
OBSERVATIONAL
Conditions
Summary
This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy. Specifically, the study aims to identify pre- vs post-treatment differences in the following domains: * cognitive performance * blood expression of biomarkers related to neurodegeneration * psychosocial wellbeing Thus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy: * neuropsychological standard assessment * blood sampling * psychosocial self-reported questionnaires
Eligibility
Inclusion Criteria2
- OSAS diagnosis (AHI > 5)
- handedness: right
Exclusion Criteria4
- previous ventilotherapy
- neurological and/or neurodegenerative conditions
- Personality disorders, autism spectrum disorders, schizophrenia, psychosis
- sleep disorders comorbidities (eg., narcolepsy)
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Interventions
Breathing support device during sleeping
Locations(1)
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NCT06312956