RecruitingNot ApplicableNCT06319560

Hydroxychloroquine in Type 2 Diabetes During Pregnancy

Hydroxychloroquine as an Adjunct Therapy in the Management of Type 2 Diabetes in Pregnancy: A Randomised Controlled Trial


Sponsor

National University of Malaysia

Enrollment

56 participants

Start Date

Mar 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare the use of hydroxychloroquine as an adjunct to the current treatment of pregnant women with Type 2 diabetes mellitus. The main questions it aims to answer are: * Does hydroxychloroquine improve the pregnancy outcomes in women with type 2 diabetes during pregnancy? * Does hydroxychloroquine improve the inflammatory markers in women with type 2 diabetes during pregnancy? Participants will be randomised into the intervention and control group. The control group will be on standard treatment where as the intervention group will receive hydroxychloroquine as an adjunct of standard treatment


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 45 Years

Inclusion Criteria2

  • Singleton
  • Pregnant women with a confirmed diagnosis of type 2 Diabetes Mellitus

Exclusion Criteria6

  • autoimmune disease such as Systemic Lupus Erythematosus or rheumatic disease
  • chronic kidney disease
  • fetal anomaly
  • women on steroid therapy
  • diabetic retinopathy
  • known thalassaemia or thalassaemia carrier

Interventions

DRUGHydroxychloroquine Oral Tablet

200mg daily


Locations(1)

Antenatal clinic, UKM Medical Centre

Cheras, Kuala Lumpur, Malaysia

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NCT06319560


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