End Stage Renal Disease Clinical Trials

96 recruitingLast updated: June 18, 2026

There are 96 actively recruiting end stage renal disease clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, Houston, Texas, United States, Dallas, Texas, United States. Updated daily from ClinicalTrials.gov.


End Stage Renal Disease Trials at a Glance

96 actively recruiting trials for end stage renal disease are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 46 trials, with the heaviest enrollment activity in Boston, Houston, and Dallas. Lead sponsors running end stage renal disease studies include Mansoura University, National Taiwan University Hospital, and Fresenius Medical Care Deutschland GmbH.

Browse end stage renal disease trials by phase

Treatments under study

About End Stage Renal Disease Clinical Trials

Looking for clinical trials for End Stage Renal Disease? There are currently 62 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new End Stage Renal Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about End Stage Renal Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 96 trials

Recruiting
Not Applicable

Pivotal Study of the Velocity™ pAVF System

Chronic Kidney DiseaseEnd Stage Renal Disease (ESRD)Hemodialysis Access+1 more
Venova Medical126 enrolled12 locationsNCT07153939
Recruiting
Phase 2

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled26 locationsNCT06712654
Recruiting
Not Applicable

CAPABLE Transplant

Quality of LifeDisability PhysicalDepression+1 more
Johns Hopkins University43 enrolled1 locationNCT06326905
Recruiting
Phase 1

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

End Stage Renal DiseaseRenal ImpairmentChronic Kidney Failure
Merck Sharp & Dohme LLC24 enrolled3 locationsNCT07348237
Recruiting

PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

End Stage Renal DiseaseHemodialysis Access Failure
Merit Medical Systems, Inc.100 enrolled7 locationsNCT06422871
Recruiting

Changes in Regional Ventilation-Perfusion Match Following Percutaneous Transluminal Angioplasty for Arteriovenous Graft Thrombosis

End Stage Renal Disease on DialysisArteriovenous Graft Thrombosis
First Affiliated Hospital of Wannan Medical College20 enrolled1 locationNCT07613632
Recruiting
Not Applicable

RaDIANT Health Systems Intervention

Kidney DiseaseEnd Stage Renal Disease (ESRD)
Indiana University14,000 enrolled5 locationsNCT07033117
Recruiting
Phase 4

Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease

End Stage Renal Disease on Dialysis
Yale University30 enrolled1 locationNCT05671991
Recruiting
Phase 4

The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis

StrokeEnd Stage Renal DiseaseAtrial Fibrillation and Flutter+1 more
Nicholas Carlson718 enrolled13 locationsNCT03862859
Recruiting
Not Applicable

An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL

End Stage Renal Disease
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's100 enrolled4 locationsNCT06032208
Recruiting
Not Applicable

Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

DiabetesEnd Stage Renal Disease
Sonavex, Inc.304 enrolled21 locationsNCT06190717
Recruiting

Calciphylaxis in Patients With Chronic Kidney Disease - A Study of the Danish Calciphylaxis Research Initiative (DanCaRI)

Chronic Kidney DiseasesEnd Stage Renal Disease (ESRD)Calciphylaxis+2 more
Odense University Hospital860 enrolled1 locationNCT07511283
Recruiting
Not Applicable

Solv Multi-Pass Hemodialysis System In-Center Clinical Study

End Stage Renal Disease
Mozarc Medical US LLC46 enrolled1 locationNCT07216885
Recruiting
Not Applicable

Light Therapy in End Stage Kidney Disease

End Stage Renal Disease
University of Pennsylvania60 enrolled1 locationNCT06310161
Recruiting
Not Applicable

Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

Arteriovenous FistulaEnd Stage Renal DiseaseKidney Disease, End-Stage
C. R. Bard280 enrolled17 locationsNCT04634916
Recruiting
Phase 3

Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.

End Stage Renal Disease
Iperboreal Pharma Srl170 enrolled41 locationsNCT03994471
Recruiting
Phase 2Phase 3

Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

End Stage Renal Disease
Roberto Gedaly78 enrolled1 locationNCT03321656
Recruiting
Not Applicable

Effect of a Plant-Focused Diet on Nutritional Status in Malnourished Peritoneal Dialysis Patients

End Stage Kidney Disease (ESRD)End Stage Renal Disease (ESRD)Peritoneal Dialysis (PD)+1 more
National University of Malaysia100 enrolled1 locationNCT07157397
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation

End Stage Renal DiseaseDelayed Graft FunctionDeceased Donor Kidney Transplant
Apellis Pharmaceuticals, Inc.320 enrolled1 locationNCT07020832
Recruiting
Not Applicable

CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients

End Stage Renal DiseaseChronic Kidney Disease Stage 5
University of Manitoba340 enrolled5 locationsNCT05726526