Zinc and Iron Absorption From Common Beans in Young Adult Women
University of California, Davis
15 participants
May 1, 2024
INTERVENTIONAL
Conditions
Summary
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents. Phytate, the storage form of phosphorus in plants, and polyphenols, which contribute to the varied colors of common beans, are natural components of the beans and can reduce zinc and iron bioavailability from these foods.
Eligibility
Inclusion Criteria6
- Healthy eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
- BMI 18.5 - 30 kg/m2
- Regular consumer of beans, i.e. ≥ 4 servings per month
- Usual iron intake estimated by Food Frequency Questionnaire to be less than the Recommended Daily Allowance (RDA) of 18 mg/d (8)
- Subject is willing and able to comply with the study protocols.
- Subject is willing to participate in all study procedures.
Exclusion Criteria10
- Dislike or allergy to beans
- Self-reported current or recent pregnancy (within the past 12 months)
- Self-reported recent termination of pregnancy (3 months if abortion in 1st or 2nd trimester, or 12 months if in 3rd trimester)
- Self-reported plans to become pregnant during the study period
- Self-reported cancer
- Self-reported surgery without the past 12 months
- Currently taking prescription drugs, other than for contraception, or any nutritional supplements
- Any daily iron supplementation within the past 12 months.
- Currently breastfeeding
- Any medical conditions affecting iron or zinc metabolism (such as hemochromatosis or sickle cell disease)
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Interventions
Bean High in Phytic Acid and High in Inhibitory Polyphenols
Bean Low in Phytic Acid and High in Inhibitory Polyphenols
Bean Low in Phytic Acid and Low in Inhibitory Polyphenols
Bean High in Phytic Acid and Low in Inhibitory Polyphenols
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06327529