RecruitingNot ApplicableNCT06328127

Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors


Sponsor

Brigham and Women's Hospital

Enrollment

400 participants

Start Date

Dec 17, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients (aged 18 years and older) undergoing allogeneic HSCT and are approaching 100-days post-HSCT
  • Ability to speak, read, and respond to questions in English or Spanish to complete study procedures
  • Access to a basic telephone

Exclusion Criteria2

  • Patients who underwent allogeneic HSCT for benign hematologic conditions
  • Patients with severe psychiatric or cognitive conditions, such as dementia, determined by their transplant oncologist to make them unable to provide informed consent or comply with study procedures

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Interventions

BEHAVIORALPATH

PATH, a phone-delivered positive psychology intervention for patients who have undergone HSCT, consists of three 3-week modules. The first module focuses on gratitude and physical activity goal setting. The second module focuses on personal strengths and resources to enhance daily physical activity. The third module focuses on meaning and assessing barriers to physical activity. The third week of each module is an integration exercise dedicated to help participants explore practical ways of incorporating the themes for the given module into daily life. A trained interventionist will guide participants to complete each 30-minute weekly session.


Locations(3)

Moffitt Cancer Center

Tampa, Florida, United States

Dana Farber Cancer Institute

Boston, Massachusetts, United States

Duke Cancer Institute

Durham, North Carolina, United States

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NCT06328127


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