Zephyr Valve Japan Post-Marketing Surveillance

This study is a post-marketing surveillance program in Japan monitoring the real-world use of the Zephyr Endobronchial Valve — a small one-way valve placed in the airways of people with severe emphysema (a form of advanced COPD — a chronic lung condition that makes breathing very difficult). The valve reduces hyperinflation in the most damaged part of the lung, allowing healthier parts to work better. This study collects safety and effectiveness data from patients in routine clinical practice. **You may be eligible if:** - Your doctor has determined that you are a suitable candidate for this valve procedure, based on Japanese medical guidelines - You recently completed pulmonary rehabilitation (within the past 6 months) - You stopped smoking at least 4 months ago - Your lung function tests meet the required thresholds - You can walk between 100 and 500 meters in a 6-minute walk test - Your breathlessness is significantly impacting daily life - Testing (Chartis system) shows the targeted lung lobe has little to no air leaking between lobes (collateral ventilation) **You may NOT be eligible if:** - There are no specific exclusion criteria listed — eligibility is based on your doctor's assessment and adherence to approved guidelines Talk to your doctor to see if this trial is right for you.