RecruitingNot ApplicableNCT06340178

CT-guided Lung Biopsy Risk Optimization Method

CT-guided Lung Biopsy Risk Optimization Method - Effect of Fluid Application in the Pleural Cavity and the Gravitational Effect of Pleural Pressure


Sponsor

Insel Gruppe AG, University Hospital Bern

Enrollment

198 participants

Start Date

Sep 29, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient positioning to allow biopsy in gravity-dependent areas of the lung.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria3

  • Ability to provide informed consent (knowledge of project languages), \>18 years.
  • Indeterminate or suspicious lung lesion unsuitable for transbronchial biopsy or Status after unsuccessful transbronchial biopsy
  • Indication for biopsy given by referring specialist (in patients).

Exclusion Criteria4

  • Preintervention bleeding into the pleural cavity
  • More than 1 lesion should be biopsied at the same time
  • Infiltration of the thoracic wall
  • Pregnancy

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Interventions

PROCEDUREFluid application during ct-guided lung biopsy

Injection of a small amount of fluid (max. 20 ml sodium chlorid) in the pleural cavity at the biopsy site


Locations(1)

Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 10

Bern, Switzerland

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NCT06340178


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