Risk Factors Clinical Trials

67 recruitingLast updated: June 18, 2026

There are 67 actively recruiting risk factors clinical trials across 34 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include Toronto, Ontario, Canada, Bethesda, Maryland, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Risk Factors Trials at a Glance

67 actively recruiting trials for risk factors are listed on ClinicalTrialsFinder across 6 cities in 34 countries. The largest study group is Not Applicable with 36 trials, with the heaviest enrollment activity in Toronto, Bethesda, and New York. Lead sponsors running risk factors studies include University of Toronto, Insel Gruppe AG, University Hospital Bern, and Consorzio Mario Negri Sud.

Browse risk factors trials by phase

Treatments under study

About Risk Factors Clinical Trials

Looking for clinical trials for Risk Factors? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Risk Factors trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Risk Factors clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 67 trials

Recruiting

Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach

Immune SystemGut MicrobiomeTransgender+1 more
Charite University, Berlin, Germany200 enrolled1 locationNCT05334888
Recruiting

Imaging Techniques in MRI

HealthyHealthy VolunteersCardiac Risk Factors
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT01130545
Recruiting
Not Applicable

Improving the Heart Health of Home Health Aides

Cardiovascular (CV) RiskCardiovascular HealthCardiovascular+1 more
Weill Medical College of Cornell University40 enrolled2 locationsNCT07067398
Recruiting
Not Applicable

Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health

Cardiovascular DiseasesCardiometabolic Risk FactorsCognition+2 more
Loughborough University16 enrolled1 locationNCT06953232
Recruiting
Phase 4

DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis

Cardiometabolic Risk FactorsCirrhosisCirrhotic Cardiomyopathy+1 more
Post Graduate Institute of Medical Education and Research, Chandigarh400 enrolled1 locationNCT07322237
Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle CellSickle Cell Cardiopulmonary ComplicationsSickle Cell Organ Damage+2 more
National Heart, Lung, and Blood Institute (NHLBI)200 enrolled1 locationNCT05213572
Recruiting
Not Applicable

Coronary Artery Disease Assessment Strategies in TAVI Patients

Coronary Artery DiseaseTranscatheter Aortic Valve ReplacementHeart Disease Risk Factors
Insel Gruppe AG, University Hospital Bern546 enrolled1 locationNCT06559332
Recruiting
Not Applicable

Cardiometabolic Health Intervention Using Movement-to-Music Exercise

Cardiometabolic Risk Factors in Adult Wheelchair Users
University of Alabama at Birmingham132 enrolled1 locationNCT05606432
Recruiting
Not Applicable

The SWITCH (Substitution of High With Low Ultra-processed Soy Protein Foods In a Guideline-based Diet inTervention for Cardiometabolic Health) Trial

Metabolic HealthHypertensionDiabetes Mellitus, Type 2+3 more
University of Toronto300 enrolled1 locationNCT06907862
Recruiting
Not Applicable

The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities

cognitive healthPreventionDementia Risk Factors
University of Coimbra100 enrolled1 locationNCT06922071
Recruiting
Not Applicable

Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health

Sedentary BehaviorCardiometabolic Risk FactorsBlood Pressure+1 more
Columbia University324 enrolled1 locationNCT05353322
Recruiting
Not Applicable

Impact of a Probiotic Supplementation With Lifestyle Modification on Liver Steatosis, Fibrosis, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Liver ElastographyLiver steatosisInsulin Resistance+2 more
Fu Jen Catholic University Hospital80 enrolled2 locationsNCT07400367
Recruiting
Phase 4

Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults

ObesityCardiometabolic Risk FactorsWeight Reduction
Asian Institute Of Medical Sciences60 enrolled1 locationNCT07513168
Recruiting
Not Applicable

Determining Efficacy of an Artificial Intelligence-based System for Heart Failure Detection Through Interpretation of Electrocardiograms (DECISION)

Heart FailureCardiovascular Risk Factors
Idoven 1903 S.L.1,968 enrolled5 locationsNCT07113223
Recruiting
Not Applicable

Using Middle School Science Teachers to Address Cancer Health Disparities

Cancer PreventionCancer Risk Factors
Weill Medical College of Cornell University1,812 enrolled5 locationsNCT07501689
Recruiting

Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring

Cardiovascular DiseasesHeart Disease Risk Factors
The University of Texas at Arlington80 enrolled1 locationNCT06150989
Recruiting
Not Applicable

Effect of Ginger Capsules on Inflammation, Oxidative Stress, and Endothelial Function

Cardiometabolic Risk FactorsOxidative StressInflammation Biomarkers
Ana Mª Garcia Munoz50 enrolled1 locationNCT07437222
Recruiting
Not Applicable

Effect of a Ginger-Based Beverage on Inflammation, Oxidative Stress, and Endothelial Function

Cardiometabolic Risk FactorsOxidative StressInflammation Biomarkers
Javier Marhuenda50 enrolled1 locationNCT07433998
Recruiting
Not Applicable

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

ObesityHypertensionOverweight+4 more
Universidad Católica San Antonio de Murcia220 enrolled1 locationNCT07447362
Recruiting
Not Applicable

Sleep and Circadian Mechanisms in Hypertension

Cardiovascular DiseasesHypertensionSleep+2 more
Oregon Health and Science University32 enrolled1 locationNCT05184933