Pneumothorax Clinical Trials

26 recruitingLast updated: June 17, 2026

There are 26 actively recruiting pneumothorax clinical trials across 12 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3. Top locations include Bethesda, Maryland, United States, Basel, Switzerland, Bern, Switzerland. Updated daily from ClinicalTrials.gov.


Pneumothorax Trials at a Glance

26 actively recruiting trials for pneumothorax are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Bethesda, Basel, and Bern. Lead sponsors running pneumothorax studies include Assiut University, Brigham and Women's Hospital, and Ain Shams University.

Browse pneumothorax trials by phase

Treatments under study

About Pneumothorax Clinical Trials

Looking for clinical trials for Pneumothorax? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pneumothorax trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pneumothorax clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 26 trials

Recruiting

Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer

Kidney CancerKidney NeoplasmsPneumothorax+1 more
National Cancer Institute (NCI)950 enrolled1 locationNCT00033137
Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

PneumothoraxLymphangioleiomyomatosisLung Disease+1 more
National Heart, Lung, and Blood Institute (NHLBI)2,000 enrolled1 locationNCT00001465
Recruiting
Not Applicable

Suction vs Underwater Seal for HemoPneumoThoraX Trial

Hemothorax; TraumaticHemopneumothorax; Traumatic
Vanderbilt University Medical Center150 enrolled1 locationNCT07551791
Recruiting
Not Applicable

16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy

PneumothoraxPleural Effusion
University Hospital, Basel, Switzerland124 enrolled1 locationNCT06958848
Recruiting

Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases

PneumothoraxCOPDPneumonia+4 more
Assiut University700 enrolled1 locationNCT06983366
Recruiting

Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting

Transient Tachypnea of the NewbornPneumothoraxRespiratory Distress Syndrome in Premature Infant+5 more
Mayo Clinic500 enrolled1 locationNCT07344714
Recruiting
Not Applicable

Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications

Postoperative Respiratory FailureMechanical PowerPostoperative Pulmonary Atelectasis+7 more
University General Hospital of Patras200 enrolled1 locationNCT07186933
Recruiting
Not Applicable

Evaluation of the Efficacy of Diagnostic Support Algorithms in Chest X-rays- LuAna Trial

PneumothoraxPleural EffusionLung Injury+3 more
Hospital Israelita Albert Einstein1,470 enrolled1 locationNCT06686251
Recruiting
Not Applicable

CT-guided Lung Biopsy Risk Optimization Method

PneumothoraxRisk FactorsRadiology, Interventional+1 more
Insel Gruppe AG, University Hospital Bern198 enrolled1 locationNCT06340178
Recruiting

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

PneumothoraxLung UltrasoundCardiac Surgery+2 more
Jacobo Moreno Garijo120 enrolled1 locationNCT07018856
Recruiting
Not Applicable

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

MesotheliomaAtelectasisPneumothorax+11 more
Brigham and Women's Hospital230 enrolled1 locationNCT06538376
Recruiting
Not Applicable

Intraoperative Paravertebral Block and Postoperative Complications

Lung Cancer (Diagnosis)Video-assisted Thoracoscopic Surgery (VATS)Pulmonary Infections+8 more
Tongji Hospital500 enrolled1 locationNCT07211529
Recruiting
Not Applicable

Feasibility and Accuracy of a Novel Pleural Drain Gas Analyzer in Detecting Air Leaks

PneumothoraxAir Leak From Lung
Lung Healing Technologies Inc33 enrolled1 locationNCT06548386
Recruiting
Not Applicable

Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial

Primary spontaneous pneumothorax
Swedish Medical Center200 enrolled1 locationNCT06411431
Recruiting
Not Applicable

Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)

Pain, PostoperativeThoracic EpiduralVATS+3 more
Maxima Medical Center366 enrolled1 locationNCT06053476
Recruiting

Utility of one-way valves in the airways to treat pneumothorax (collapse of the lung) that can help in shortening the duration of stay in hospital.

Secondary pneumothoraxPneumothorax
Institute of Respiratory Health40 enrolled1 locationACTRN12625000360415
Recruiting

A pilot study to assess a lung function tests as a monitoring tool in patients with pneumothorax.

Traumatic pnuemothoraxPrimary spontaneous pneumothoraxPneumothorax+2 more
Institute of respiratory health40 enrolled1 locationACTRN12625000235404
Recruiting
Phase 2

Non-steroidal Anti-inflammatory Drugs in Pleurodesis

Pain ManagementPneumothoraxPleurodesis+1 more
Centre Hospitalier Universitaire, Amiens358 enrolled1 locationNCT06731647
Recruiting

Clinical Characteristics and Outcome of Patients Xith Spontaneous Pneumothorax

Spontaneous Pneumothorax
Sohag University100 enrolled1 locationNCT06644820
Recruiting
Not Applicable

Outpatient Management of Primary Spontaneous Pneumothorax: Pigtail Catheter With Unidirectional Valve vs. Exsufflation, Randomized Prospective Study

Pneumothorax, Spontaneous
Rennes University Hospital188 enrolled5 locationsNCT03691480