RecruitingNCT06341166

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse: the SCIMITAR Trial


Sponsor

Centro Cardiologico Monzino

Enrollment

300 participants

Start Date

Jun 19, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a multicenter, observational prospective and retrospective study which aims are: 1) to compute a scoring model potentially predictive for the diagnosis of fibrosis by CMR in patients with MVP; 2) to identify specific features that may predispose to ≥ mild VAs or SCD in patients with MVP.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • age ≥ 18 years
  • Echocardiographic diagnosis of mitral valve prolaspe, defined as a systolic displacement of one or both mitral leaflets ≥ 2 mm above the plane of the mitral valve annulus in long-axis views

Exclusion Criteria4

  • age< 18 years
  • coexistence of other cardiomyopathies or other ≥ moderate valve diseases
  • scarce acoustic transthoracic echocardiographic window
  • usual contraindications for cardiac magnetic resonance

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Locations(1)

Centro Cardiologico Monzino

Milan, Milan, Italy

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NCT06341166


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