Mitral valve prolapse Clinical Trials

11 recruitingLast updated: May 6, 2026

There are 11 actively recruiting mitral valve prolapse clinical trials across 10 countries. Studies span Not Applicable, Phase 3. Top locations include Los Angeles, California, United States, New York, New York, United States, Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Mitral valve prolapse Trials at a Glance

11 actively recruiting trials for mitral valve prolapse are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Los Angeles, New York, and Cleveland. Lead sponsors running mitral valve prolapse studies include Central Hospital, Nancy, France, Centre Hospitalier Universitaire, Amiens, and Annetine Gelijns.

Browse mitral valve prolapse trials by phase

Treatments under study

About Mitral valve prolapse Clinical Trials

Looking for clinical trials for Mitral valve prolapse? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mitral valve prolapse trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mitral valve prolapse clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Not Applicable

Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring

Mitral valve prolapseVentricular Arrythmia
Universitaire Ziekenhuizen KU Leuven60 enrolled1 locationNCT06378996
Recruiting

Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse

Mitral valve prolapse
Centro Cardiologico Monzino300 enrolled1 locationNCT06341166
Recruiting

AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D Ultrasound

Mitral valve prolapseMyxomatous Mitral Valve Degeneration
IRCCS Policlinico S. Donato150 enrolled1 locationNCT07384871
Recruiting

Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery

Mitral valve prolapseVentricular TachycardiaMitral Regurgitation
Karolinska Institutet90 enrolled1 locationNCT06255457
Recruiting
Not Applicable

PRIMARY Ancillary Substudy

Ventricular arrhythmiasMitral valve prolapseLeft Ventricular Fibrosis
Annetine Gelijns250 enrolled25 locationsNCT07103733
Recruiting
Phase 3

Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse

Mitral valve prolapseVentricular Arrhythmias and Cardiac Arrest
Oslo University Hospital50 enrolled1 locationNCT05631730
Recruiting

Patient-Centered Approach for Treatment Decisions in Mitral Valve Prolapse

Mitral valve prolapse
Northwell Health150 enrolled5 locationsNCT06738537
Recruiting

Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.

Left ventricular noncompactionHypertrophic Cardiomyopathy (HCM)Non-ischemic Cardiomyopathy+12 more
Scientific Institute San Raffaele15,000 enrolled1 locationNCT06607471
Recruiting

Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Mitral valve prolapseMitral Plasty
Centre Hospitalier Universitaire, Amiens1,500 enrolled1 locationNCT03113552
Recruiting
Not Applicable

STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2

Mitral valve prolapse
Central Hospital, Nancy, France280 enrolled1 locationNCT04852731
Recruiting

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System

Mitral valve prolapseHeart Valve DiseasesMitral Regurgitation+2 more
NeoChord500 enrolled5 locationsNCT04190602